Many of us may already be aware that when it comes to heart disease in the U.S., Black, African American, and Afro-Caribbean communities are disproportionately affected compared to other racial and ethnic groups.* But did you know about three to four percent of African Americans carry a mutation in the TTR gene (V122I) that makes it more likely that they may develop ATTR-CM, however not all carriers develop the disease. ATTR-CM gets worse over time, which is why early diagnosis and management are so important.